中國有色金屬學報(英文版)
Transactions of Nonferrous Metals Society of China
| Vol. 16 No. 6 December 2006 |
YI Jian-min(易健民)1, 2, ZHANG Guo-li(張國麗)1
（1. School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China;
2. Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang 414000, China）
Abstract: Based on chemical thermodynamics and mass balance, countercurrently fractional chiral extraction by hollow fiber membrane was investigated. The mathematical modules for the relation of chiral extraction yield and product optical purity with number of transfer units by chiral extraction with hollow fiber membrane were established, and the modules were simulated by visual basic(VB) proceduce. The results show that, the difference in free energy between two diastereomeric complexes formed by R- and S-enantiomer with chiral selector, ??(?G), is the force of separation of enantiomers. It is necessary to separate enantiomers, where one of the extraction factors is above 1, and the other is below 1. Under certain phase ratio, chiral separation depends on separation factor and number of transfer units. The experimental result is in agreement with the theoretical value.
Key words: fractional chiral extraction; mathematical modules; VB simulation
